At Meril Genomics Laboratory, we offer Whole Genome Sequencing (WGS), the most comprehensive genomic analysis available. By decoding 100% od your DNA-including coding and non-coding regions-WGS provides unparalleled insights into genetic health, hereditary risks , and personalized medicine. Whether for diagnosing elusive conditions, predicting disease susceptibility, or advancing research, our WGS service empowers precision healthcare decisions.
Whole Genome Sequencing (WGS)
Unlocking the Full Potential of Your Genome
Whole Genome Sequencing (WGS): Key Features
Full Genome Coverage
Sequences 3.2 billion base pairs, capturing exons, introns, regulatory regions, and structural variants.
Disease-Associated Variants
Identifies mutations linked to:
- Rare genetic disorders (e.g., spinal muscular atrophy, mitochondrial diseases).
- Hereditary cancers (BRCA1/2, APC, MLH1).
- Neurodegenerative conditions (Alzheimer's, Parkinson's).
- Cardiovascular, autoimmune, and metabolic diseases
Pharmacogenomics
Analyzes 200+ drug-response genes (e.g., CYP2C19, VKORC1) to optimize
medication safety and efficiency.
Carrier Status
Screens for 500+ recessive conditions (e.g., cystic brosis, sickle cell anemia).
Non-Coding Insights
Detects regulatory variants, lncRNAs, and epigenetic markers.
Technical Excellence
High Coverage Sequencing:
30x coverage ensures robust detection of SNVs, CNVs, indels, and structural rearrangements.
Advanced Bioinformatics:
Validated under CAP/CLIA and ISO 15189 standards.
Key Advantages
Ultimate Comprehensiveness
Surpasses exome sequencing by analyzing the entire genome.
Future-Ready Data
Raw genomic data stored for reanalysis as science evolves.
Family Health Insights
Identifies inherited risks for proactive family screening.
Research Applications
Supports population studies, biomarker discovery, and novel variant identification.
Limitations
Higher Cost
More expensive than targeted panels or WES.
Complex Interpretation
Non-coding variants may require functional studies.
VUS Challenges
Higher likelihood of variants of uncertain significance.
How it Works?
01.
Sample Collection
Simple blood draw or saliva collection kit.
02.
DNA Extraction & Library Prep
High-quality DNA isolation and fragmentation for sequencing.
03.
Whole Genome Sequencing
Genemap generates billions of
reads for complete genome assembly.
04.
Bioinformatics Analysis
Proprietary pipelines align sequences, call variants, and annotate findings using global databases (ClinVar, dbSNP, COSMIC).
05.
Interpretation & Reporting
•ACMG/AMP guidelines classify variants.
•Clinical reports include diagnostic findings, drug-gene interactions, and family risk assessment.
06.
Delivery
Results delivered to clinicians in 6–8 weeks.
Who Should Consider WGS?
Patients
- Undiagnosed genetic conditions despite prior testing (e.g., WES, panels).
- Family history of complex or multi-generational diseases.
- Proactive individuals seeking lifelong genomic insights.
Clinicians
- Solving diagnostic odysseys in pediatrics or adult medicine.
- Proactive individuals seeking lifelong genomic insights.
Researchers
- Studying genomic variations in rare diseases or diverse populations.
Our Testing Options
Diagnostic Findings
- Pathogenic variants (e.g., FBN1 mutation → Marfan syndrome).
- Risk alleles for polygenic conditions (e.g., APOE ε4 → Alzheimer's risk).
Pharmacogenomic Report
- Guidance on 200+ medications (e.g., avoid statins for SLCO1B1 poor transporters).
Carrier Status
- Reproductive risks and recommendations for partners.
Research Add-Ons
- Optional analysis of non-coding regions or novel variants.
Book Your Whole Genome Sequencing
Step into the future of genomics medicine with Meril WGS
Price
Contact Us
Turnaround Time
6-8 weeks
Contact
Via Healthcare provider
Testing must be ordered by a healthcare provider.
Speak to your physician or connect with our genetic counselling team.
Complies with HIPAA, GDPR and ACMG. Raw data and reanalysis service available
Your genome, Decoded-transforming health and today and tomorrow
Have any questions?
We are here to answer